Can topiramate cause acute angle closure glaucoma?

Conclusions: Topiramate may be associated with ciliochoroidal effusion with forward displacement of the lens-iris diaphragm and anterior chamber shallowing, resulting in acute myopia and angle-closure glaucoma.

Why does topiramate cause angle closure glaucoma?

21-24 Topiramate-induced ciliochoroidal effusion with forward displacement of the lens-iris diaphragm causes extreme anterior chamber shallowing, resulting in angle-closure glaucoma.

Which drug is contraindicated in angle closure glaucoma?

Sulfa-based drugs (acetazolamide, hydrochlorothiazide, cotrimoxazole, and topiramate) can cause acute angle closure glaucoma by ciliary body edema with anterior rotation of the iris-lens diaphragm. Iridotomy is not effective.

Can Topamax cause eye problems?

Topamax can cause severe eye conditions that may result in blindness. Acute myopia, which causes nearsightedness, can cause headaches or blurred vision because of increased pressure in the eye.

Can topiramate cause eye pressure?

Results: A 27-year-old female patient developed decreased vision in both eyes due to acute myopia 2 weeks of after initiating therapy with topiramate. Emergency department evaluation revealed visual acuities of 20/400 right eye and 20/200 left eye. Intraocular pressures were 33 mm Hg right eye and 26 mm Hg left eye.

When should you not take Topamax?

chronic kidney disease stage 3B (moderate) chronic kidney disease stage 4 (severe) chronic kidney disease stage 5 (failure) kidney disease with likely reduction in kidney function.

Can you take Ambien if you have glaucoma?

Anxiolytics/sedatives/hypnotics (applies to Ambien) glaucoma Some hypnotic drugs can have an anticholinergic effect and should be used with caution in patients with glaucoma, and trouble urinating due to retention or enlarged prostate.

Can you take Wellbutrin with glaucoma?

Conclusions and Relevance Both bupropion and topiramate are widely prescribed drugs. The risk of angle-closure glaucoma in patients younger than 50 years was twice as high in patients taking bupropion and more than 5 times higher in patients taking topiramate.

Is Topamax bad for glaucoma?

Ocular adverse effects reported as attributable to Topiramate are: acute angle closure glaucoma, ocular pain, headache, hyperaemia, mydriasis, uveitis, visual field defects, acute onset myopia, suprachoroidal effusions, blepharospasm, oculogyric crisis, scleritis, and retinal haemorrhage [5].

What are the symptoms of angle closure glaucoma?

Acute angle-closure glaucoma

• Severe headache.
• Eye pain.
• Nausea and vomiting.
• Blurred vision.
• Halos around lights.
• Eye redness.

What should not be taken with Topamax?

People should not drink alcohol or take sedatives or tranquilizers, such as Valium and Xanax, while taking Topamax. Topamax suppresses the activity of the enzyme, carbonic anhydrase, in the body.

Does topiramate cause acute angle closure glaucoma?

Topiramate was first implicated as a cause of bilateral acute angle closure glaucoma in a case report by Banta, et al. in July of 2001 [2]. A recent review of case reports of adverse effects of topiramate use revealed abnormal vision, acute secondary angle closure glaucoma, acute myopia and suprachoroidal effusions [3].

Does Topamax cause glaucoma?

Topiramate, brand name Topamax, is an anticonvulsant drug that is used for seizure, migrane and neuropathic pain. It is a sulfamate-substituted monosaccharide. Other sulfa based drugs such as acetazolamide, hydrocholorothiazide and cotrimoxazole have been associated with secondary angle closure glaucoma [1].

Should suspicion for medication induced angle closure glaucoma be higher?

Suspicion for medication induced angle closure glaucoma should be higher whenever angle closure presents bilaterally. We present two cases of bilateral angle closure glaucoma secondary to topiramate.

What is Topamax used to treat?

Topiramate, brand name Topamax, is an anticonvulsant drug that is used for seizure, migrane and neuropathic pain. It is a sulfamate-substituted monosaccharide. Other sulfa based drugs such as acetazolamide, hydrocholorothiazide and cotrimoxazole have been associated with secondary angle closure glaucoma.