Does ganciclovir cover CMV?

Ganciclovir and valganciclovir are used primarily in treating cytomegalovirus (CMV) infections. In vitro synergy with foscarnet has been observed against CMV [3].

How is congenital CMV treated?

For babies with signs of congenital CMV infection at birth, antiviral medications, primarily valganciclovir, may improve hearing and developmental outcomes. Valganciclovir can have serious side effects and has only been studied in babies with signs of congenital CMV infection.

Is there any treatment for CMV infection in pregnancy?

There’s currently no treatment for CMV in pregnancy, but in most cases the virus does not cause any problems for your baby. Antiviral medicine may be used to treat: babies diagnosed with congenital CMV after they’re born. people with a weakened immune system.

Which trimester is associated with the highest risk of congenital CMV?

The risk of transmission from mother to baby is highest if she gets a primary CMV infection in the third trimester (40-70%) and is lowest if the primary infection begins in the first or second trimesters (30-40%).

Is CMV treatable?

CMV spreads from person to person through body fluids, such as blood, saliva, urine, semen and breast milk. There is no cure, but there are medications that can help treat the symptoms.

How many babies are born with congenital CMV?

About one out of every 200 infants is born with congenital cytomegalovirus (CMV) infection. Around one in five babies born with congenital CMV infection will have long-term health problems.

How common is CMV in newborns?

In the United States, about 1% of infants are infected with CMV before birth. This happens because the mother had a first-time CMV infection or a reactivated infection during her pregnancy. An infected mother can pass the virus to her child before, during, or after birth.

What birth defects are caused by CMV?

Babies who are infected with CMV before birth are at higher risk of several defects such as microcephaly (small head size), hepatomegaly (enlarged liver), jaundice (yellow color of skin and eyes), anemia (low blood count), pneumonia, seizures, vision loss, and hearing loss and others.

What are the side effects of ganciclovir?

Ganciclovir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• nausea.
• vomiting.
• diarrhea.
• constipation.
• stomach pain.
• belching.
• loss of appetite.
• changes in ability to taste food.