The Daily Insight
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What is intrathecal spasticity control?

A: Intrathecal Baclofen Therapy (ITB) is a treatment using Lioresal® Intrathecal (baclofen) that is delivered into the fluid around your spinal cord (intrathecal) to help manage severe spasticity. For long term treatment, the drug is placed into a pump that is surgically placed under the skin of your abdomen.

What is intrathecal form?

Intrathecal chemotherapy is a form of cancer treatment in which a healthcare professional injects chemotherapy drugs into the cerebrospinal fluid (CSF). This colorless fluid surrounds the brain and spinal cord, which form the central nervous system (CNS), to protect them from injuries.

What is intrathecal solution?

Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF) and is useful in spinal anesthesia, chemotherapy, or pain management applications.

What is a intrathecal port?

An intrathecal portal (or port) is an implanted device that allows access to the intrathecal space in your spine. It is used for the delivery of medications for pain management. A port is a small, stainless steel disc (about the size of a half dollar) with a raised “septum” in the center.

What are the side effects of intrathecal baclofen?

A: The side effects of Lioresal® Intrathecal can include drowsiness, lightheadedness, dizziness, nausea and vomiting, low blood pressure, headache, seizures, and loose muscles.

What is intrathecal baclofen?

Intrathecal baclofen is used to help relax certain muscles in your body. It relieves the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, cerebral palsy, or certain injuries to the spine.

Where is intrathecal?

Also known as the subarachnoid space, the intrathecal space is the fluid-filled area located between the innermost layer of covering (the pia mater) of the spinal cord and the middle layer of covering (the arachnoid mater).

Why is intrathecal preservative free?

All medications used for epidural or intrathecal analgesia must be preservative – free. Medication preservatives can be neurotoxic and may cause spinal cord injury. In addition, alcohol is potentially neurotoxic and may not be used to clean vial tops or injection ports.

What is the most common potential complication of intrathecal baclofen therapy?

Potentially life-threatening complications of ITB therapy include overdose and withdrawal syndrome. In addition, infections, wound dehiscence, seroma, cerebrospinal fluid leak, and mechanical problems related to the pump and catheter can occur, which can cause life-threatening complications (6), as seen in our patient.

What are externalized intrathecal catheters used for?

Some practitioners tunnel these catheters under the skin for some distance to provide stability and reduce the likelihood of inadvertent catheter withdrawal. Currently, the U.S. Food and Drug Administration (FDA) has not approved any externalized intrathecal catheters, and it is common to use epidural or lumbar drain catheters for this purpose.

Can intrathecal catheter be used for post-dural puncture headache (PDPH)?

An intrathecal catheter can also be used to prevent post-dural puncture headache (PDPH) following an accidental dural puncture during epidural anesthesia (e.g., in parturients). Through this approach, the catheter can be used to provide analgesia (local anesthetics) and gets removed after at least 24 hours.

Where do you place an intrathecal introducer?

The introducer is inserted below the level of the conus medullaris which is typically above L2 in adults. Figure 41-24 shows a patient in the left lateral position with the C-arm providing a PA view for placement of the intrathecal introducer.

What are the benefits of intrathecal therapy?

With proven efficacy, intrathecal therapy quickly came into use for the management of intractable pain for both cancer and non-cancerous pain. An intrathecal catheter can also be used to prevent post-dural puncture headache (PDPH) following an accidental dural puncture during epidural anesthesia (e.g., in parturients).