What is Transcutol HP?
Transcutol® HP (diethylene glycol monoethyl ether) is the highest-purity grade solvent and solubilizer for solubility and bioavailability enhancement for oral and alternative routes (parenteral, nasal, ophthalmic formulations).
What is diethylene glycol monoethyl ether used for?
Used to make soaps, dyes, and other chemicals. Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent.
Is diethylene glycol monoethyl ether safe?
Results: Diethylene glycol monoethyl ether when used in a 99.9+% pure pharmaceutical grade is safe and well tolerated. Up to half of the applied solvent crosses the skin’s barrier and becomes systemic. For certain drug actives, this solvent provides for an intracutaneous depot.
Is diethylene glycol an ether?
Diethylene glycol butyl ether (2-(2-Butoxyethoxy)ethanol) is an organic compound, one of several glycol ether solvents. It is a colorless liquid with a low odour and high boiling point.
Is dipropylene glycol good for oily skin?
Many cosmetic ingredients do more harm to acne instead of clearing it. But propylene glycol is safe for acne as it is not oily.
Is diethylene glycol monoethyl ether flammable?
ICSC 0039 – DIETHYLENE GLYCOL MONOETHYL ETHER. Combustible. Above 96°C explosive vapour/air mixtures may be formed. NO open flames.
Is there glycol in vodka?
Alcohol is an amazing substance – it’s a natural preservative and does not need any additives, especially petrochemical-derived ingredients that could cause health problems. Propylene Glycol has absolutely no place in vodka.
Is DPG skin safe?
DPG is a type of organic chemical compound that’s used as the solvent in most fragrances. The fragrance-grade version is useful because it’s odorless, colorless, has a high boiling point and a low toxicity. It won’t add any unnecessary odor to your fragrance, and it’s safe to use on your skin.
What is the structure of didiethylene glycol monoethyl ether?
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether.
What is transtranscutol® P?
Transcutol® P is a high purity grade of diethylene glycol monoethyl ether (DEGEE) (Figure 1) manufactured by the condensation of ethylene oxide and ethanol, followed by distillation. The presence of an ether and an alcohol function explains the exceptional solubilizing capacity of this solvent.
Is diethylene glycol a primary alcohol or secondary alcohol?
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol. 2- (2-ethoxyethoxy)ethanol Computed by LexiChem 2.6.6 (PubChem release 2019.06.18)
What grade of Transcutol should I use?
For topical formulations Gattefossé recommends the use of Transcutol® P grade for human medicines and Transcutol® V for veterinary medicines. Note that Transcutol® HP is the highest purity grade and is preferred for oral medicines and for highly sensitive APIs.
